{"opportunitySpacesMenu":{"title":"Bioenergetic Engineering","subTitle":"Opportunity space","exploreText":"Explore this space","image":null,"imageMobile":null,"backLink":{"isActive":false,"text":"Back to Opportunity spaces","href":"/opportunity-spaces","title":"Back to Opportunity spaces"},"signUpLink":{"isActive":false,"text":"Sign up for updates","href":"/sign-up-for-updates-qa","title":""},"items":[{"title":"Overview","link":{"isActive":true,"text":"Bioenergetic Engineering","href":"/opportunity-spaces/bioenergetic-engineering","title":"Bioenergetic Engineering"}}],"activeBackgroundColor":"#ffcd9b"},"modules":[{"type":"op-header","image":{"src":"/media/clplgrjj/untitled-34.png?rmode=pad&format=webp&quality=100","alt":"Untitled 34"},"title":"Bioenergetic Engineering","intro":"Genetic engineering now lets us control life’s information, yet the engineering of life’s energy remains underdeveloped. A powerful set of new tools could bridge the gap, enabling breakthroughs ranging from treatments for neurodegenerative disease to biohybrid solutions for environmental remediation and resilience.","text":"","colour1":"blue","colour2":"yellow","btnColour":"blue","breadcrumb":[{"isActive":false,"text":"Home","href":"/home","title":""},{"isActive":false,"text":"Opportunity spaces","href":"/opportunity-spaces","title":""},{"isActive":true,"text":"Bioenergetic Engineering","href":"/opportunity-spaces/bioenergetic-engineering","title":""}],"links":{"opLink":{"isActive":true,"text":"Bioenergetic Engineering","href":"/opportunity-spaces/bioenergetic-engineering","title":""},"programmeLinks":[],"seedLinks":[]},"hideGradient":false},{"type":"standout-copy","title":"What is an opportunity space?","text":"<p><span class=\"p3\">Opportunity spaces are areas of research that we believe are ripe for breakthroughs. They are defined by our Programme Directors, and must be highly consequential for society, under-explored relative to its potential impact, and ripe for new talent, perspectives, or resources to change what’s possible.</span></p>","link":null,"color":null,"isWhiteText":false,"fullWidth":false},{"type":"technical-areas","title":"Core beliefs","text":"The core beliefs that underpin this opportunity space:","items":[{"label":"1.","title":"","text":"<p>While information has been the major focus of modern biology, energy and information are both fundamental to life →<strong> bioenergetic engineering has the potential to catalyse advances on the scale of the genetic revolution.</strong></p>"},{"label":"2.","title":"","text":"<p>Life uses powerful energy building blocks, like ATP, that are unlike any used in engineering → <strong>leveraging these primitives will enable a range of bio-hybrid devices and other systems whose performance far exceeds today’s best designs.</strong></p>"},{"label":"3.","title":"","text":"<p>The feedback loop between engineering disciplines and fresh insights is accelerating → <strong>we’re at an inflection point where scientists and engineers from many disciplines can begin treating life’s energy machinery as a design space.</strong></p>"}]},{"type":"rich-text-content","text":"<div class=\"technical-areas container\">\n<h5 class=\"technical-areas__intro__title h5 aos-init aos-animate\" style=\"margin-bottom: 10px;\" data-aos=\"fade\">Observations</h5>\n<p style=\"margin-top: 0; margin-bottom: 20px;\" class=\"technical-areas__intro__text p3\">Some signposts as to why we see this area as important, underserved, and ripe.</p>\n<div class=\"technical-areas__area aos-init aos-animate\" data-aos=\"fade-right\" data-aos-delay=\"0\">\n<figure style=\"margin: 0 auto; display: inline-block; text-align: center;\"><img style=\"width: 100%; height: auto; margin-top: 30px;\" src=\"/media/zg1djvg2/aria-bioenergetic-opp-space_observations.jpg?rmode=max\" alt=\"Observations image\"></figure>\n</div>\n</div>","mediumLayout":false,"fullWidth":false},{"type":"rich-text-content","text":"<div>\n<div class=\"container aos-init aos-animate\" data-aos=\"fade-right\">\n<div class=\"rte\">\n<p style=\"text-align: center;\">Download as a PDF <a rel=\"noopener\" href=\"/media/bbgltbs2/aria-bioenergetic-engineering-opportunity-spacepdf.pdf\" target=\"_blank\" title=\"Bioenergetic Engineering opportunity space [PDF]\">here</a>, or the accessible version <a rel=\"noopener\" href=\"/media/r1mpuntj/bioenergetic-engineering-opp-space_accessible.pdf\" target=\"_blank\" title=\"Accessible Bioenergetic Engineering opportunity space  [PDF]\">here</a>.</p>\n</div>\n</div>\n</div>","mediumLayout":false,"fullWidth":false},{"type":"standout-copy","title":"Give feedback on this opportunity space","text":"<p>Help inform the development of the programme thesis.</p>","link":{"target":"_blank","isActive":true,"text":"Share your thoughts ","href":"https://forms.monday.com/forms/149f7b3cd0feeb6121bdac42cbd61588?r=euc1","title":"fill in the form to have your say"},"color":"c7e9fb","isWhiteText":false,"fullWidth":false},{"type":"spacer-comp","cssSizeClass":"medium","height":0},{"type":"team-cards","items":[{"image":{"src":"/media/402pmlqf/nathan-1.jpg?width=1000&height=1000&format=webp&v=1dbdb7e3f6cf8b0","alt":"Headshot of Nathan Wolfe"},"name":"Nathan Wolfe","text":"Nathan is a renowned virologist, epidemiologist, and entrepreneur. Most recently, he was a Visiting Scholar in Stanford's Bioengineering Department, having previously founded initiatives to quantify epidemic and pandemic risk, and coordinate scientists globally to spot emerging pathogens. He served on DARPA’s Defense Sciences Research Council.","position":"Programme Director"},{"image":{"src":"/media/z2zffgve/sarath.jpg?width=1000&height=1000&format=webp&v=1dbbe8400403510","alt":"Sarath"},"name":"Sarath Murugan","text":"Sarath joined ARIA from a business operations and strategy role a defence engineering scale-up, where his team developed a product that brought the capabilities of gen-AI to the disconnected-edge. He holds an LLB from Bristol, and has experience in project and product-facing roles. Sarath supports ARIA as an operating partner from Pace.","position":"Programme Specialist"},{"image":{"src":"/media/c14lo0hv/ryanolf1.jpeg?rxy=0.5338545254760395,0.4411937302851597&width=1000&height=1000&format=webp&v=1dbc3dea9232390","alt":"Ryanolf"},"name":"Ryan Olf","text":"Ryan is a Caltech and Berkeley-trained physicist with a varied and voracious technical appetite. His previous adventures include creating the world’s lowest-entropy quantum gas, designing nanotube-based GLP-1 implants, automating gene therapy manufacturing, and developing software for his family’s village shop.","position":"External technical advisor"}],"title":"Meet the programme team","text":"<p>Our Programme Directors are supported by a Programme Specialist (P-Spec) and Technical Specialist (T-Spec); this is the nucleus of each programme team. P-Specs co-ordinate and oversee the project management of their respective programmes, whilst T-Specs provide highly specialised and targeted technical expertise to support programmatic rigour.</p>"},{"type":"spacer-comp","cssSizeClass":"medium","height":0},{"type":"standout-copy","title":"Our other opportunity spaces","text":"<p>Our opportunity spaces are designed as an open invitation for researchers from across disciplines and institutions to learn with us and contribute – a variety of perspectives are just what we need to change what’s possible.</p>","link":{"isActive":false,"text":"Discover our opportunity spaces","href":"/opportunity-spaces","title":""},"color":"c7e9fb","isWhiteText":false,"fullWidth":false},{"type":"spacer-comp","cssSizeClass":"medium","height":0}],"scriptsAtTop":"<!-- Start cookieyes banner --> <script id=\"cookieyes\" type=\"text/javascript\" src=\"https://cdn-cookieyes.com/client_data/eae9957b4a0acd8b0ca247e2/script.js\"></script> <!-- End cookieyes banner -->\n\n<!-- Google tag (gtag.js) -->\n<script async src=\"https://www.googletagmanager.com/gtag/js?id=G-QB5LXNMKJN\"></script>\n<script>\n  window.dataLayer = window.dataLayer || [];\n  function gtag(){dataLayer.push(arguments);}\n  gtag('js', new Date());\n\n  gtag('config', 'G-QB5LXNMKJN');\n</script>\n\n<style>\n.biography-swiper,\n.team-cards {\n    margin-bottom: 60px;\n}\n.quick-link__label {\ndisplay: none;\n}\n.site-footer__logo img {\n filter: invert(1);\n}\n\n.rte-image-text {\n  display: flex;\n  align-items: flex-start;\n  gap: 80px;\n  max-width: 1000px;\n  margin: 0 auto 50px;\n}\n\n.rte-image-text__image {\n  flex: 0 0 300px;\n}\n\n.rte-image-text__text {\n  flex: 1;\n}\n\n@media (max-width: 800px) {\n  .rte-image-text {\n    flex-direction: column;\n    align-items: center;\n    gap: 20px;\n  }\n\n  .rte-image-text__image {\n    flex: 0 0 auto;\n        width: 100%;\n        height: auto;\n  }\n  .rte-image-text__image img {\n    height: auto;\n  }\n}\n\n:target {\n    scroll-margin-top: 140px;\n}\n\n.media-text__caption {\nfont-size: 14px !important\n}\n</style>\n\n<!--intercom-->\n<div data-intercom-id=\"i5uhzwkf\"></div>\n\n<script>\nsetTimeout(() => {window.dispatchEvent(new Event('resize'));}, 500);\n</script>","scriptsAtBottom":"","id":3045,"languageCode":"en","pageName":"Bioenergetic Engineering","scrollSmoothness":0.0,"gtmCode":"GTM-T8Z5F55","topNav":{"logo":{"text":"ARIA - 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