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They each serve as a bedrock for multi-year programmes directed by our Programme Directors, as well as additional flares of seed funding to support researchers pursuing bold ideas.

Even if you are new to a topic, we urge you to dive in below – a variety of perspectives are just what we need to change what’s possible.

","link":{"target":"","isActive":false,"text":"Discover funding opportunities in these spaces","href":"/funding-opportunities","title":""},"color":null,"isWhiteText":false,"fullWidth":false},{"type":"op-grid","items":[{"image":{"src":"/media/1p0jpenj/sculptinginnateimmunity_opheader.png?width=350&height=700&format=webp&v=1dbd4762f6a0bb0","alt":"Sculptinginnateimmunity Opheader"},"title":"Sculpting Innate Immunity","text":"As the body’s first line of defence, the innate immune system has enormous therapeutic potential, sensing and initiating responses to infection, injury, metabolic stress, and chronic inflammation. Modulating innate immunity with precision and accuracy could unlock a new paradigm in human health.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/sculpting-innate-immunity","title":"Visit the Sculpting Innate Immunity opportunity space"}]},{"image":{"src":"/media/vtjlbmtg/cropv7.png?width=350&height=700&format=webp&v=1dbbe9203c36000","alt":"Butterfly"},"title":"Bioenergetic Engineering","text":"Genetic engineering now lets us control life’s information, yet the engineering of life’s energy remains underdeveloped. A powerful set of new tools could bridge the gap, enabling breakthroughs ranging from treatments for neurodegenerative disease to biohybrid solutions for environmental remediation and resilience.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/bioenergetic-engineering","title":"Visit the Bioenergetic Engineering opportunity space"}]},{"image":{"src":"/media/lgmkvrf4/frame-54.png?width=350&height=700&format=webp&v=1db4c89f6328c60","alt":" A cut-out graphic of half of a brain. "},"title":"Scalable Neural Interfaces","text":"Neurological and neuropsychiatric disorders have overwhelming societal and economic impacts. We need to build highly targeted, minimally invasive technologies that enable us to interface, at scale, with the human brain.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/scalable-neural-interfaces","title":"Visit the Scalable Neural Interfaces opportunity space"},{"isActive":false,"text":"Programme: Precision Neurotechnologies ","href":"/opportunity-spaces/scalable-neural-interfaces/precision-neurotechnologies","title":"Explore the programme"},{"isActive":false,"text":"Opportunity seeds ","href":"/opportunity-spaces/scalable-neural-interfaces/scalable-neural-interfaces","title":"in the Scalable Neural Interfaces opportunity space"}]},{"image":{"src":"/media/msfpn3xm/programmable_plants.png?width=350&height=700&format=webp&v=1db4c89e4e1dec0","alt":"A cut-out photo of a piece of corn."},"title":"Programmable Plants","text":"Plants enable human life and offer solutions to key challenges like food insecurity, climate change, and environmental degradation. Programmable plants can secure our future, ensuring food and a sustainable biosphere for future generations.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/programmable-plants","title":"Visit the Programmable Plants opportunity space"},{"isActive":false,"text":"Programme: Synthetic Plants ","href":"/opportunity-spaces/programmable-plants/synthetic-plants","title":"Explore the programme"},{"isActive":false,"text":"Opportunity seeds ","href":"/opportunity-spaces/programmable-plants/programmable-plants","title":"in the Programmable Plants opportunity space"}]},{"image":{"src":"/media/ymwfbzfk/mathematicsai.png?width=350&height=700&format=webp&v=1db31da1a587d40","alt":"Mathematicsai"},"title":"Mathematics for Safe AI","text":"We don’t yet have known technical solutions to ensure that powerful AI systems interact as intended with real-world systems and populations. A combination of scientific world-models and mathematical proofs may be the answer to ensuring AI provides transformational benefit without harm.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/mathematics-for-safe-ai","title":"Visit the Mathematics for Safe AI opportunity space"},{"isActive":false,"text":"Programme: Safeguarded AI ","href":"/opportunity-spaces/mathematics-for-safe-ai/safeguarded-ai","title":"Explore the programme"},{"isActive":false,"text":"Opportunity seeds ","href":"/opportunity-spaces/mathematics-for-safe-ai/mathematics-for-safe-ai","title":"in the Mathematics for Safe AI opportunity space"}]},{"image":{"src":"/media/kbtb4fql/naturecomputesbetter.png?width=350&height=700&format=webp&v=1db31da5d86aba0","alt":"Naturecomputesbetter"},"title":"Nature Computes Better","text":"We can redefine the way computers process information by exploiting principles found ubiquitously in nature. In doing so, we can better understand how the natural world around us performs computation and build dramatically more efficient computers.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/nature-computes-better","title":"Visit the Nature Computes Better opportunity space"},{"isActive":false,"text":"Programme: Scaling Compute ","href":"/opportunity-spaces/nature-computes-better/scaling-compute","title":"Explore the programme"},{"isActive":false,"text":"Opportunity seeds ","href":"/opportunity-spaces/nature-computes-better/nature-computes-better","title":"in the Nature Computes Better opportunity space"}]},{"image":{"src":"/media/j4plgown/aria_scopingourplanet_image_177x354.png?width=350&height=700&format=webp&v=1db4c877c69dc50","alt":"A graphic of half of a camera lens."},"title":"Scoping Our Planet","text":"Our understanding of the Earth system is limited by serious measurement and modelling gaps that lead to uncertainties in weather and climate predictions. By cultivating frontier technologies, we can fill these gaps and equip society to better respond to the climate crisis.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/scoping-our-planet","title":"Visit the Scoping Our Planet opportunity space"},{"isActive":false,"text":"Programme: Forecasting Tipping Points ","href":"/opportunity-spaces/scoping-our-planet/forecasting-tipping-points","title":"Explore the programme"},{"isActive":false,"text":"Opportunity seeds ","href":"/opportunity-spaces/scoping-our-planet/opportunity-seeds","title":"in the Future Proofing Our Climate and Weather opportunity space"}]},{"image":{"src":"/media/eswhqpud/smartrobotbodies.png?width=350&height=700&format=webp&v=1db31dc6889f780","alt":"Smartrobotbodies"},"title":"Smarter Robot Bodies","text":"Throughout history, humans have used tools and machines to reduce the burden of physical labour. We are entering a new era with robots smart enough to act independently in complex and dynamic environments. But to reap the benefits of smarter machines, we need smarter bodies.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/smarter-robot-bodies","title":"Visit the Smarter Robot Bodies opportunity space"},{"isActive":false,"text":"Programme: Robot Dexterity ","href":"/opportunity-spaces/smarter-robot-bodies/robot-dexterity","title":"Explore the programme"},{"isActive":false,"text":"Opportunity seeds ","href":"/opportunity-spaces/smarter-robot-bodies/smarter-robot-bodies","title":"in the Smarter Robot Bodies opportunity space"}]},{"image":{"src":"/media/3fhd32tz/futureproofingplanet.png?width=350&height=700&format=webp&v=1db31dc98c75cd0","alt":"Futureproofingplanet"},"title":"Future Proofing Our Climate and Weather","text":"If an abrupt alteration in a climate system were to unfold, we would have no tools to mitigate the effects. Through research, we could understand the science behind how we might intervene to responsibly manage the climate and weather. ","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/future-proofing-our-climate-and-weather","title":"Visit the Future Proofing Our Climate and Weather opportunity space"},{"isActive":false,"text":"Programme: Exploring Climate Cooling ","href":"/opportunity-spaces/future-proofing-our-climate-and-weather/exploring-climate-cooling","title":"Explore the programme"}]},{"image":{"src":"/media/4bcdx1e2/aria_manufacturingabundance-no-line-copy.png?width=350&height=700&format=webp&v=1dcbb9707ca5a70","alt":"Aria Manufacturingabundance No Line Copy"},"title":"Manufacturing Abundance","text":"Ages of human history are defined by materials that transformed societies and mark breakthroughs in mastery over matter. Rather than a single material, the next age will be defined by our ability to assemble molecules into bespoke solutions for today’s challenges and unlock sustainable abundance.","info":"","links":[{"isActive":false,"text":"Discover more ","href":"/opportunity-spaces/manufacturing-abundance","title":"Explore the Manufacturing Abundance opportunity space"},{"isActive":false,"text":"Programme: Universal Fabricators ","href":"/opportunity-spaces/manufacturing-abundance/universal-fabricators","title":"Explore the Universal Fabricators programme"}]}]},{"type":"quick-link-anchor","anchorName":"emergingareas"},{"type":"spacer-comp","cssSizeClass":"medium","height":0},{"type":"standout-copy","title":"Sign up for updates","text":"

Keep up-to-date on the progress of our existing and emerging opportunity spaces.

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